MS PATHS stands for Multiple Sclerosis Partners Advancing Technology and Health Solutions. MS PATHS uses advances in technology to generate and collect standardized patient data during routine office visits. Information gathered from patients at participating MS centers will enable research that could potentially lead to new discoveries in MS.
The MS PATHS vision is to form a technology-enabled network of MS centers through which researchers have access to patient data generated from a broad MS population. Using these data, we hope to gain powerful insights and continuously learn more about MS. Ultimately, MS PATHS aims to better quantify the value of treatment and improve patient outcomes in MS.
Patient information currently exists in diverse forms (such as lab tests or MRIs) and may be collected in different ways by different MS centers. With such variations, it is difficult to meaningfully compare information from across the MS population and to identify underlying trends.
To help address these variations, components of MS PATHS are integrated into routine office visits at participating MS centers. Relevant patient data are generated and collected for research in an efficient and standardized way.
With the aid of new technology, MS PATHS aims to overcome the challenges of accurately and consistently monitoring subtle changes in various aspects of MS over time, providing a more holistic view of MS.
MRI protocols and sequencing are standardized within and among partici-pating MS centers This standardization can enable longitudinal comparisons and data sharing across these centers and facilitate research that could lead to the development of quantitative MRI measures of MS disease severity and activity.
As part of routine care, patients use a tablet-based device designed to objectively quantify the major motor, visual, and cognitive symptoms and quality of life outcomes associated with MS.
Aggregated information can be used for research that could potentially lead to new discoveries in MS.
Patients may be asked to contribute in other options ways, such as providing blood samples for the Biobanking substudy.
MS PATHS takes patient privacy seriously. Only encoded aggregated data are shared with researchers participating in MS PATHS. This means steps have been taken to secure the data and protect patients’ identities. Data include information such as arm and hand function, vision, walking speed, and MRI.
MS PATHS is sponsored by Biogen, a leading biotechnology company focused on developing therapies for neurodegenerative and autoimmune disorders.
MS PATHS brings together MS centers with a shared commitment to enhancing care for MS patients.
For more information about MS PATHS at Johns Hopkins Medicine, please contact Sandra Cassard, ScD, Research Associate, at firstname.lastname@example.org.
For more information about MS PATHS at Washington University in St. Louis, please contact Dana Perantie, CCRC, Clinical Research Coordinator, at email@example.com.
Researchers participating in MS PATHS will have access to data generated electronically and collected through MS PATHS that can enable research and continuous learning. The goal is to share insights with the broader MS community as more is learned about MS.
• Reliable, objective, and standardized outcome measures
• Information to support MS treatment decision making and monitoring
• Evidence to one day support individualized decision making at the point of care
As of December 2020, researchers from MS PATHS have generated 12 manuscripts and more than 80 congress presentations.
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