Seeking to enhance MS care

MS PATHS stands for Multiple Sclerosis Partners Advancing Technology and Health Solutions. MS PATHS uses advances in technology to generate and collect standardized patient data during routine office visits. Information gathered from patients at participating MS centers will enable research that could potentially lead to new discoveries in MS.

Vision

The MS PATHS vision is to form a technology-enabled network of MS centers through which researchers have access to patient data generated from a broad MS population. Using these data, we hope to gain powerful insights and continuously learn more about MS. Ultimately, MS PATHS aims to better quantify the value of treatment and improve patient outcomes in MS.

About us

MS PATHS is sponsored by Biogen, a leading biotechnology company focused on developing therapies for neurodegenerative and autoimmune disorders.

Participating MS centers

MS PATHS brings together MS centers with a shared commitment to enhancing care for MS patients.

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Cemcat

For more information about MS PATHS at CEMCAT, please contact Oriol Nualart, Data manager, +34 93 175 15 55+34 93 175 15 55 or onualart@cem-cat.org.

Cleveland Clinic

For more information about MS PATHS at Cleveland Clinic, please contact Malory Weber, Clinical Project Manager, at (216) 444-4625 (216) 444-4625 or weberm9@ccf.org.

Cleveland Clinic - Lou Ruvo Center for Brain Health

For more information about MS PATHS at Cleveland Clinic - Lou Ruvo Center for Brain Health, please contact Laurinda Keelen, CCRC, Clinical Research Coordinator, at (702)701-7941 (702)701-7941 or Keelenl@ccf.org .

Johns Hopkins Medicine

For more information about MS PATHS at Johns Hopkins Medicine, please contact Sandra Cassard, ScD, Research Associate, at mscenter@jhmi.edu.

NYU Langone

For more information about MS PATHS at NYU Langone, please contact Kai Sherman, Assistant Director of Research, at (646) 501-7531 (646) 501-7531 or kai.sherman@nyumc.org.

OhioHealth

For more information about MS PATHS at OhioHealth, please contact Erin Woodburn, CCRC, Clinical Research Coordinator, at (614) 788-6075 (614) 788-6075 or erin.woodburn@ohiohealth.com.

Carl Gustav Carus

For more information about MS PATHS at University Hospital Carl Gustav Carus, please contact Dr. Anja Dillenseger, +49-351-458-5661 +49-351-458-5661 or Anja.Dillenseger@uniklinikum-dresden.de .

University of Rochester

For more information about MS PATHS at University of Rochester, please contact Jean Sauvain, CCRC, Clinical Research Coordinator at, (585)273-3688(585)273-3688 or Jean_sauvain@urmc.rochester.edu.

Washington University in St. Louis

For more information about MS PATHS at Washington University in St. Louis, please contact Dana Perantie, CCRC, Clinical Research Coordinator, at dperantie@wustl.edu.

Better understanding MS

Patient information currently exists in diverse forms (such as lab tests or MRIs) and may be collected in different ways by different MS centers. With such variations, it is difficult to meaningfully compare information from across the MS population and to identify underlying trends.

To help address these variations, components of MS PATHS are integrated into routine office visits at participating MS centers. Relevant patient data are generated and collected for research in an efficient and standardized way.

With the aid of new technology, MS PATHS aims to overcome the challenges of accurately and consistently monitoring subtle changes in various aspects of MS over time, providing a more holistic view of MS.

Sharing insights

Researchers participating in MS PATHS will have access to data generated electronically and collected through MS PATHS that can enable research and continuous learning. The goal is to share insights with the broader MS community as more is learned about MS.

We hope to create:

  • Reliable, objective, and standardized outcome measures
  • Information to support MS treatment decision making and monitoring
  • Evidence to one day support individualized decision making at the point of care

Scientific Output from MS PATHS

As of May 2020, researchers from MS PATHS have generated 9 manuscripts and more than 80 congress presentations.

Links to published manuscripts are available on the following page...

Network-wide Manuscripts

  • Mowry E, et al. Harnessing Real-world Data to Inform Decision-making: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) Front Neurol 2020. View here
  • Rao SM et al Multiple Sclerosis Performance Test: Validation of Self-Administered Neuroperformance Modules. Eur J Neurol 2020. View here
  • Wang J et al Socioeconomic status and race are correlated with affective symptoms in multiple sclerosis. Multiple Sclerosis and Related Disorders 2020. View here
  • Rhodes JK et al Multiple Sclerosis Performance Test: Technical Development and Usability. Adv Ther 2019. View here
  • Shirani A et al on behalf of the Multiple Sclerosis Partners Advancing Technology and Health Solutions Investigators. The association between handedness and clinicodemographic characteristics in people with multiple sclerosis: a brief report. Mult Scler J Exp Trans Clin 2019. View here
  • Rao SM et al Processing speed test: Validation of a self-administered, iPad®-based tool for screening cognitive dysfunction in a clinic setting. MSJ 2017. View here

Site-Specific Manuscripts

  • Macaron G et al Cognitive processing speed in multiple sclerosis clinical practice: association with patient- reported outcomes, employment, and MRI metrics. Eur J Neurology 2020. View here
  • Macaron G et al Technology-enabled assessments to enhance multiple sclerosis clinical care and research. Neurology Clinical Practice 2019. View here
  • Fitzgerald K et al Validation of the SymptoMScreen with performance-based or clinician-assessed outcomes. Multiple Sclerosis and Related Disorders. 2019 View here

MS PATHS takes patient privacy seriously. Only encoded aggregated data are shared with researchers participating in MS PATHS. This means steps have been taken to secure the data and protect patients' identities. Data include information such as arm and hand function, vision, walking speed, and MRI.

Contact Us:
Biogen | 225 Binney Street | Cambridge, MA 02142 | Phone: 781-464-2000781-464-2000